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Thursday, February 12, 2009

An article in the February 12 issue of the New England Journal of Medicine reports on an unusual cause for an outbreak of low blood sugar among men in Singapore: illegal use of sexual performance enhancement drugs that were contaminated with a diabetes drug.

Between January and May 2008, 149 men and one woman between 19 and 97 (mean age 51) were admitted to five public hospitals for unexplained low blood sugar. Similar cases were reported in media reports from Hong Kong. Seven Singaporean patients remained in a coma because of prolonged sugar starvation of the brain, and four subsequently died. The diabetes drug glyburide was found in blood and/or urine samples in 85% of cases; 30% admitted having used illegal sexual performance enhancers.

The contaminated products were a counterfeit version of the drug Cialis (meant for the treatment of genuine erectile dysfunction), and three purported herbal preparation (the affected brands included Power 1 Walnut and Santi Bovine Penis Erecting Capsule). All four preparations additionally contained Viagra in varying concentrations. Two herbal products contained traces of the weight loss drug sibutramine, a compound related to amphetamines.

The drug packaging mentioned names of non-existent overseas production facilities, so the source of the contamination with the diabetes drug could not be established.

The authors underline the risks that is known to be associated with purchasing drugs from unreliable providers or from online resellers. The clandestine use of impotence drugs as sexual performance enhancers seems to have provided a good illustration of this problem. They further call for more efforts by national and international health and law enforcement agencies to curb the manufacturing, international transport and sales of untrustworthy medication.

Sunday, June 11, 2017

While Theresa May remains Prime Minister of Britain, her party, the Conservative Party, won Thursday’s general election but lost its majority in Parliament.

The next scheduled general election was not until 2020. May requested this general election, called a snap election, in April, when polls indicated it would strengthen the then-slight majority the Conservatives held in Parliament. Talks to establish the specifics of Britain’s departure from the European Union are set to begin June 19. Last year, British voters decided to leave the EU, but many of the specifics of the United Kingdom’s new relationship with the rest of Europe have yet to be established. May and the other Conservatives favor a “hard Brexit”, in which Britain would lose its current level of access to Europe’s single market and have to deal with higher tariffs and more complicated customs processes but it would regain full control of its borders with respect to trade and immigration. An increase in the number of Conservative Parliamentary seats would have supported this plan.

“Officially Theresa May is still the partner in Brexit negotiations,” said senior German MP Stephan Meyer, “but the political reality is different after this disastrous defeat. I can’t imagine that May will be able to remain prime minister.”

Jean-Claude Juncker of the European Commission said, “As far as the Commission is concerned we can open negotiations tomorrow morning at half past nine […] First we have to agree on the divorce and exit modalities, and then we have to envisage the architecture of our future relations. I do hope that the result of the elections will have no major impact on the negotiations we are desperately waiting for.”

A Parliamentary majority requires 326 of the organisation’s 650 seats. The Conservative Party holds 318 outright, including May’s own seat in Maidenhead, and the Labour Party holds 262, having gained about 30 in this election. In Britain, the leader of whichever political party has the most seats becomes Prime Minister, though they are also formally appointed by the monarch. Theresa May became leader of the Conservative Party on July 11 of last year and was appointed by Queen Elizabeth II two days later. Cases in which no political party wins outright are called a hung Parliament, and then two or more parties rule together in coalition. Britain had a coalition government from 2010 to 2015. Northern Ireland’s Democratic Unionist Party has pledged an unofficial alliance with the Conservatives, which would bring them up to 328.

This would make May the second Prime Minister in a row to call an election with unexpected results. David Cameron called for a referendum on Britain’s EU membership, not expecting the voters would reject it.

May’s current ministry said most of her senior officials, including Treasurer Philip Hammond, Foreign Secretary Boris Johnson, and Home Secretary Amber Rudd, will remain in the Cabinet.

May met with Queen Elizabeth II yesterday to request her permission to form a government in her name, a traditional formality.

Tuesday, January 26, 2010

The mystery of the location of a viewpoint used by English painter John Constable has been solved, after nearly 200 years. The Stour Valley and Dedham Church was painted in Suffolk, England, between 1814 and 1815, but changes to the landscape meant that the spot he chose was not known, despite the best efforts of historians and art experts.

Now the puzzle has been answered. Martin Atkinson, who works for the National Trust as property manager for East Suffolk, used clues from the painting and looked at old maps to track down the viewpoint. Trees had grown, a hedgerow had been planted and boundaries had moved or disappeared, but Atkinson eventually worked out where Constable had stood. He said, “When I discovered that I had worked out the location where Constable painted this particular masterpiece, I couldn’t believe it. All the pieces of the jigsaw finally fitted together.”

Atkinson used an 1817 map of East Bergholt, where Constable grew up, as a reference point, but found that the view would have changed not long after the painting was completed. “The foreground didn’t fit at all, it was quite unusual as we know Constable painted it in the open air so he would have been standing in the scene. The hedgerow in his work no longer exists and there’s another hedgerow that runs across the scene today which wasn’t there. When you stand on the road on which he would have stood, and use the oak tree as a reference point, you see the same view. It’s great to see where an old master stood – and be inspired by the same view,” he said.

Suffolk, where Constable painted many of his finest paintings, is often called “Constable country”. Most, but not all, of the locations that Constable depicted are known. The picture is now housed in the Museum of Fine Arts, Boston, Massachusetts.

Tuesday, February 6, 2007

San Jose, California –Cell phones, cigarette lighters and glowsticks are raised in tribute as Circle of Life begins playing. Soon cheers drown out the song as the multicoloured performers appear on stage. A somewhat unusual introduction; but this is no ordinary show, and these are no ordinary attendees. This is Further Confusion, the second largest furry convention in the world.

The volunteer organizers have something to cheer about, too; Furry fans have gathered from far and wide at the DoubleTree Hotel to indulge their love of anthropomorphics, and Further Confusion’s 9th year is its largest, with a paid attendance of 2061. Their gains mirror those of Midwest FurFest, a similar convention held in Schaumburg, Illinois which grew 35% last November.

Both events feature art shows and auctions, live puppetry performance, masquerades, variety shows, games and parades, as well as panels that range from science and technology to society, sex and spirituality. Filling out the schedule, the hotel walls are lined with announcements of public and private room parties for separate groups. At night, the disco floor fills with dancing cats, dogs, and dragons.

For some, dressing up plays a large part of the convention – almost 300 brought a full costume. There are few professional mascots here, though, and only one or two of the costumes would be recognized by even the most avid cartoon-watcher. Instead, each act is planned and performed by other attendees, wearing “fursuits” of their own design. Many play off the year’s secret-agent theme — “Fur Your Eyes Only”.

Other fans seem content to restrict themselves to small accessories — perhaps some combination of paws, ears, or tail. Each fur bears a 3″x2″ badge detailing their personal character, or “fursona“. Often these characters are better-known than the people who play them.

It may seem lighthearted, even frivolous, but these conventions are becoming big business. Furry fans spent over $180,000 for lodging during the five days (Jan 18-22) of Further Confusion, and another $50,000 at the art auction. Attendees also purchase all manner of merchandise from attending dealers and artists, from on-the-spot art commissions and comic books of all ratings to prints, sculptures, and plush toys – even their very own fluffy tail.

Of course, any business has risk, and conventions can drain wallets when the sums just don’t add up. The first furry con, ConFurence in Southern California, ran successfully for over a decade, but cost its new organizer an estimated $60,000 in its last four years due to falling attendance before folding in 2003.

Anthropomorphic Arts and Education board member Peter Torkelson says that won’t happen to Further Confusion. Indeed, the convention ran a healthy surplus of almost $30,000 on $125,000 revenue last year, allowing it to pay off the last of its old debts and save for the future. As Torkelson explains: “The idea is if for some reason, say an earthquake happens, and it cripples the revenue stream, the convention will be able to survive into the next year. It does help our staff to know that we have [a reserve].”

The reserve also gives AAE the financial flexibility to fund charities throughout the year, a big part of its 501(c)(3) mandate. Over the nine years of the convention, attendees have raised over $60,000 for a variety of animal sanctuaries, wildlife refuges, and the Comic Book Legal Defense Fund.

Further Confusion’s hopes for the future are high. Chairwoman Laura Cherry noted that, unlike previous years, the board has “gone all out” for next year’s tenth anniversary, booking as many rooms as the hotel could offer. The host for 2009 has yet to be decided, but for many fans the question was not whether the current hotel will reach a limit, but when – and where – the convention will find a new home.

Sunday, June 26, 2005

The median house price in the United States plunged 6.5% in May to $217,000. In February of 2005, the median price of a home was $237,300.

The Economist newspaper said in its June 16th issue; “In other words, it looks like the biggest bubble in history.” by way of reference to what is happening with housing prices in the USA and much of Europe.

Japan provides an example of how a boom can turn to bust. Property prices have dropped for 14 years in a row (40% from their peak in 1991); and yet, the rise in prices in Japan during the decade before 1991 was less than the increase over the past ten years in most of today’s “housing boom” countries.

The total value of residential property rose by more than $30 trillion over the past five years in developed economies, an increase equivalent to 100% of the combined GDPs of those countries. This increase dwarfs all previous house-price booms and is greater than the global stockmarket bubble in the late 1990s. Much of the recent housing activity is being driven by speculative demand. The National Association of Realtors (NAR) reported that 23% of all American houses bought in 2004 were for investment, not for owners to live in. Another 13% were bought as second homes. NAR also found that 42% of all first-time buyers made no down-payment on their home purchase last year.

Many investors are buying solely because they think prices will keep rising, which is a warning sign of a financial bubble. In Miami, Florida, as many as half of the original buyers resell new apartments even before they are built, and properties can change hands two or three times before somebody finally moves in.

Britain’s Royal Institution of Chartered Surveyors (RICS) reported prices have been falling for ten consecutive months. Forty nine percent of their surveyors reported falling prices in May. This was the weakest report since 1992 during Britain’s previous house-price bust.

Tuesday, February 26, 2008

A result is expected today on the possibility of an election re-run in Nigeria. Opposition parties claim that current President Umaru Yar’Adua’s People’s Democratic Party (PDP) fixed the results of the 2007 election in his favour and are calling to have the result annulled. So far, the tribunal has rejected one out of the two petitions calling for the annulment.

International suspicions were also raised at the time, with some voicing concern over the election.

A Nigerian judge is currently delivering the ruling on the case of granting the opposition parties a re-run, neither of which claim to have won the previous election. The decision could have negative impacts – if another election is called, it could be seen as an admittance of a ‘false democracy’ occurring in the last election and therefore undermining the political process in Nigeria. However, if no re-run of the election is called, it could cause instability between political rivals and may spark protests.

Emma Esau, of the Alliance for Credible elections, told the BBC: “We have faith the judges will give us a good ruling, and in any case we don’t believe there will be violence after the decision is announced. This will not take Nigeria to the brink.”

Yar’Adua assumed office on 29th May 2007 after the election in April, where he won 70% of the vote. Since then, he has became the first Nigerian leader to declare his personal assets, as well as overturning hikes in petroleum and tax made by the previous government. Despite these positive steps, he has also been surrounded by controversy, with several governors who served him before 2007 being charged by the EFCC, the anti-corruption commission.

Election annulments have already been passed for seven of thirty-six state governors and even the senate president, David Mark.

Monday, May 11, 2009

On May 9, Moscow heralded its celebrations of Victory Day with one of the largest military parades seen since the fall of the Soviet Union through the Red Square and the streets of Moscow. Signifying the defeat over Nazi Germany in 1945 in World War 2, Victory Day continues to be one of the most poignant and emotional celebrations and national holidays in Russia. Estimates of more than 27 million lost lives during the war continues to leave a vein of sadness in Russia.

Victory day began early in Moscow with inner city streets being closed from 6am and the major entrance of Tverskaya Ulitsa completely locked down with all access to non-military blocked until the end of the parade. Tens of thousands of people lined the upper parts of Tverskaya to see the exit of the military as well as the air force fly-over on their entrance to Red Square. In total more than 9,000 troops, 69 planes and a huge collection of armored vehicles, tanks, and massive anti-aircraft missile defense systems ensured that Moscovites and the rest of Russia will remember Victory Day 2009.

In scenes reminiscent of the end of the war military bands played around the city until all hours of the night. At Leningradsky station departing veterans and widows danced and celebrated with younger generations whilst loudly singing the national anthem. As trains departed, staff handed out flowers in recognition of the contributions made and loud cheers were heard across the many platforms. In a touching event it seemed to bond the generations of yesterday and today.

Preparations for the military parade began months ago with regular rehearsals in Alabino including the erection of a mock Red Square and Kremlin to ensure authenticity. Final dress rehearsals took place in Moscow on May 7 including a full practice of the air show. On display for the first time was the S-400 air defense system which is capable of intercepting airborne targets at ranges up to 400 kilometers (249 mi).

Following the official parades and ceremonies, Red Square and the the inner city was opened to the public, albeit under extreme security and an ever watching eye from Interior Ministry troops. During the afternoon there was an estimated crowed of over 100,000 which entered Red Square to admire the parade ground and decorations, including the official stand for the dignitaries.

Closing the festivities was a series of fireworks in fourteen different locations throughout Moscow including the grand display over the Kremlin and Red Square.