Cleveland, Ohio clinic performs US’s first face transplant

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Cleveland, Ohio clinic performs US’s first face transplant
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Thursday, December 18, 2008

A team of eight transplant surgeons in Cleveland Clinic in Ohio, USA, led by reconstructive surgeon Dr. Maria Siemionow, age 58, have successfully performed the first almost total face transplant in the US, and the fourth globally, on a woman so horribly disfigured due to trauma, that cost her an eye. Two weeks ago Dr. Siemionow, in a 23-hour marathon surgery, replaced 80 percent of her face, by transplanting or grafting bone, nerve, blood vessels, muscles and skin harvested from a female donor’s cadaver.

The Clinic surgeons, in Wednesday’s news conference, described the details of the transplant but upon request, the team did not publish her name, age and cause of injury nor the donor’s identity. The patient’s family desired the reason for her transplant to remain confidential. The Los Angeles Times reported that the patient “had no upper jaw, nose, cheeks or lower eyelids and was unable to eat, talk, smile, smell or breathe on her own.” The clinic’s dermatology and plastic surgery chair, Francis Papay, described the nine hours phase of the procedure: “We transferred the skin, all the facial muscles in the upper face and mid-face, the upper lip, all of the nose, most of the sinuses around the nose, the upper jaw including the teeth, the facial nerve.” Thereafter, another team spent three hours sewing the woman’s blood vessels to that of the donor’s face to restore blood circulation, making the graft a success.

The New York Times reported that “three partial face transplants have been performed since 2005, two in France and one in China, all using facial tissue from a dead donor with permission from their families.” “Only the forehead, upper eyelids, lower lip, lower teeth and jaw are hers, the rest of her face comes from a cadaver; she could not eat on her own or breathe without a hole in her windpipe. About 77 square inches of tissue were transplanted from the donor,” it further described the details of the medical marvel. The patient, however, must take lifetime immunosuppressive drugs, also called antirejection drugs, which do not guarantee success. The transplant team said that in case of failure, it would replace the part with a skin graft taken from her own body.

Dr. Bohdan Pomahac, a Brigham and Women’s Hospital surgeon praised the recent medical development. “There are patients who can benefit tremendously from this. It’s great that it happened,” he said.

Leading bioethicist Arthur Caplan of the University of Pennsylvania withheld judgment on the Cleveland transplant amid grave concerns on the post-operation results. “The biggest ethical problem is dealing with failure — if your face rejects. It would be a living hell. If your face is falling off and you can’t eat and you can’t breathe and you’re suffering in a terrible manner that can’t be reversed, you need to put on the table assistance in dying. There are patients who can benefit tremendously from this. It’s great that it happened,” he said.

Dr Alex Clarke, of the Royal Free Hospital had praised the Clinic for its contribution to medicine. “It is a real step forward for people who have severe disfigurement and this operation has been done by a team who have really prepared and worked towards this for a number of years. These transplants have proven that the technical difficulties can be overcome and psychologically the patients are doing well. They have all have reacted positively and have begun to do things they were not able to before. All the things people thought were barriers to this kind of operations have been overcome,” she said.

The first partial face transplant surgery on a living human was performed on Isabelle Dinoire on November 27 2005, when she was 38, by Professor Bernard Devauchelle, assisted by Professor Jean-Michel Dubernard in Amiens, France. Her Labrador dog mauled her in May 2005. A triangle of face tissue including the nose and mouth was taken from a brain-dead female donor and grafted onto the patient. Scientists elsewhere have performed scalp and ear transplants. However, the claim is the first for a mouth and nose transplant. Experts say the mouth and nose are the most difficult parts of the face to transplant.

In 2004, the same Cleveland Clinic, became the first institution to approve this surgery and test it on cadavers. In October 2006, surgeon Peter Butler at London‘s Royal Free Hospital in the UK was given permission by the NHS ethics board to carry out a full face transplant. His team will select four adult patients (children cannot be selected due to concerns over consent), with operations being carried out at six month intervals. In March 2008, the treatment of 30-year-old neurofibromatosis victim Pascal Coler of France ended after having received what his doctors call the worlds first successful full face transplant.

Ethical concerns, psychological impact, problems relating to immunosuppression and consequences of technical failure have prevented teams from performing face transplant operations in the past, even though it has been technically possible to carry out such procedures for years.

Mr Iain Hutchison, of Barts and the London Hospital, warned of several problems with face transplants, such as blood vessels in the donated tissue clotting and immunosuppressants failing or increasing the patient’s risk of cancer. He also pointed out ethical issues with the fact that the procedure requires a “beating heart donor”. The transplant is carried out while the donor is brain dead, but still alive by use of a ventilator.

According to Stephen Wigmore, chair of British Transplantation Society’s ethics committee, it is unknown to what extent facial expressions will function in the long term. He said that it is not certain whether a patient could be left worse off in the case of a face transplant failing.

Mr Michael Earley, a member of the Royal College of Surgeon‘s facial transplantation working party, commented that if successful, the transplant would be “a major breakthrough in facial reconstruction” and “a major step forward for the facially disfigured.”

In Wednesday’s conference, Siemionow said “we know that there are so many patients there in their homes where they are hiding from society because they are afraid to walk to the grocery stores, they are afraid to go the the street.” “Our patient was called names and was humiliated. We very much hope that for this very special group of patients there is a hope that someday they will be able to go comfortably from their houses and enjoy the things we take for granted,” she added.

In response to the medical breakthrough, a British medical group led by Royal Free Hospital’s lead surgeon Dr Peter Butler, said they will finish the world’s first full face transplant within a year. “We hope to make an announcement about a full-face operation in the next 12 months. This latest operation shows how facial transplantation can help a particular group of the most severely facially injured people. These are people who would otherwise live a terrible twilight life, shut away from public gaze,” he said.

Posted on December 14th 2018 in Uncategorized

FEMA official in New Orleans blasts agency’s response

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FEMA official in New Orleans blasts agency’s response
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Sunday, October 23, 2005

Marty Bahamonde, the only FEMA emplyee in New Orleans during hurricane Katrina, testifying before the Senate Homeland Security and Governmental Affairs Committee, contradicts former FEMA director Michael Brown’s testimony and says Brown ignored his pleas for help.

In an August 31 Blackberry email:

“Sir, I know you know that this situation is past critical. Here are some things you might not know. Hotels are kicking people out, thousands gathering in the streets with no food or water. Hundreds still being rescued from homes” and “medical staff at the Dome expect to run out of oxygen in about 2 hours”

In an email from one of Brown’s aids:”Please schedule Joe Scarborough this evening… Also, it is very important that time is allowed for Mr. Brown to eat dinner. Gievn[sic] that Baton Rouge is back to normal, restaurants are getting busy”

Posted on December 14th 2018 in Uncategorized

Acting teacher and director Milton Katselas dies at age 75

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Acting teacher and director Milton Katselas dies at age 75
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Tuesday, October 28, 2008

Acting teacher and director Milton Katselas died Friday at age 75, after suffering from heart failure at Cedars-Sinai Medical Center in Los Angeles, California. He began the Beverly Hills Playhouse in 1978 and taught acting classes there to noted actors including George Clooney and Gene Hackman. Katselas is survived by a sister and two brothers.

Katselas directed an off-Broadway production of Edward Albee‘s The Zoo Story, and received a Tony Award nomination for his 1969 direction of Butterflies are Free. Actress Blythe Danner won a Tony Award for her role in Butterflies are Free under Katselas’ direction. He moved to California to direct the film version of that play, and went on to direct films and television movies. Actress Eileen Heckart received an Academy Award for her role in the film version of Butterflies are Free.

Katselas directed the San Francisco and Los Angeles productions of the play P.S. Your Cat Is Dead! by playwright James Kirkwood, Jr. In his author’s notes in the publication of the script, Kirkwood acknowledged Katselas, and wrote that the plays were “directed with incredible energy and enthusiasm by Milton Katselas, to whom I am extremely indebted”.

Katselas directed the television movie Strangers: Story of a Mother and Daughter, and actress Bette Davis received an Emmy Award for her role in the movie. Katselas taught many famous actors including Michelle Pfeiffer, Richard Gere, Robert Duvall, Jack Lemmon, Al Pacino, Goldie Hawn, Christopher Walken, Burt Reynolds, George C. Scott, Elizabeth Taylor, Richard Burton, Alec Baldwin, and Patrick Swayze. Katselas was credited with being able to nurture actors with raw talent so that they could develop strong Hollywood careers. He utilized innovative techniques in his courses – one course called “Terrorist Theatre” had a simple premise: successfully get an acting role within six weeks or leave the course.

He grew up in Pittsburgh, Pennsylvania to parents who had immigrated from Greece, and graduated from Carnegie Mellon. He studied acting with Lee Strasberg in New York at the Actors Studio, and received advice from directors Joshua Logan and Elia Kazan.

Katselas was a prominent Scientologist, and a July 2007 profile on Katselas in The New York Times Magazine observed that some of his students stopped taking courses at the Beverly Hills Playhouse because they felt they had been pressured to join the Church of Scientology. According to the article, Katselas credited Scientology founder L. Ron Hubbard “for much of his success in life”, and one of his students works at Scientology’s Celebrity Centre. The article commented that some in Los Angeles view the Beverly Hills Playhouse as “a recruitment center for Scientology”.

Katselas met L. Ron Hubbard after moving to California, and began studying Scientology in 1965. The New York Times Magazine reported that he had reached the level of “Operating Thetan, Level 5, or O.T. V.” in 2007. According to The New York Times Magazine when Scientologists proceed up the “The Bridge to Total Freedom” they learn the story of Xenu, and that: “75 million years ago the evil alien Xenu solved galactic overpopulation by dumping 13.5 trillion beings in volcanoes on Earth, where they were vaporized, scattering their souls.” A Church of Scientology publication, Source, lists Katselas as reaching O.T. V. in 1989.

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He is brilliant, and knows me so well as a person and an actress that he gets the most out of me.

Though some actors felt pressured to join the Church of Scientology after taking courses at the Beverly Hills Playhouse, at least one individual felt Katselas was not active enough with the organization. Actress Jenna Elfman left the Beverly Hills Playhouse because she felt Katselas was not committed enough to Scientology. Katselas had previously directed Elfman in half of Visions and Lovers: Variations on a Theme, two one-act plays about relationships that he had written himself. In 1999 Katselas had planned to adapt the script of Visions and Lovers to a film version, and Elfman was set to reprise her role from the play. In an article in Variety about the project, Elfman commented on her experience working with Katselas: “He is brilliant, and knows me so well as a person and an actress that he gets the most out of me.”

Other prominent Scientologist actors who have studied under Katselas include Giovanni Ribisi, Jason Lee, and Leah Remini. According to Rolling Stone, Katselas also recruited actress Kelly Preston to Scientology. Actress Nancy Cartwright (the voice of Bart Simpson), told Scientology publication Celebrity that Katselas motivated her to get more active in Scientology, and she stated she took the organization’s “Purification Rundown” and her life “took off completely”.

Life is an endless unspooling of art, of acting, of painting, of architecture. And where did I learn that? From Milton.

Anne Archer was introduced to Scientology while studying at the Beverly Hills Playhouse, as was former Scientologist and now outspoken critic actor Jason Beghe. Beghe told Roger Friedman of FOX News in April 2008 that “He [Katselas] gets kickbacks”, and that he was brought to a Scientology center by fellow Beverly Hills Playhouse classmate Bodhi Elfman, Jenna Elfman’s husband. In a 1998 article for Buzz Magazine, Randye Hoder wrote “In his class, Katselas is careful not to label anything as a tenet of Scientology, but there is no question that the church’s influence seeps into the playhouse.”

Anne Archer’s husband and fellow Scientologist, producer Terry Jastrow, commented to The New York Times Magazine that Katselas changed the way he experiences life on a day-to-day basis: “I go out in the world and look at human behavior now. I see a woman or man interacting with a saleslady, and I see the artistry in it. Life is an endless unspooling of art, of acting, of painting, of architecture. And where did I learn that? From Milton.”

Actor Anthony Head of Buffy the Vampire Slayer spoke highly of Katselas in a 2002 interview with San Francisco Chronicle: “He’s this wonderfully intuitive teacher and his premise is basically: The only real barriers are the ones we put in front of ourselves. If you say, ‘My character wouldn’t do that’ — bollocks! Ultimately it’s you who wouldn’t say that. Who knows what your character might do.” In the acknowledgements of her 2004 autobiography Are You Hungry, Dear?: Life, Laughs, and Lasagna, actress Doris Roberts wrote: “I thank my friend and acting teacher, the incredible Milton Katselas, for his insights, wisdom, and inspiration, which have helped make me the actress that I am.”

I really care about the craft of acting. It’s absolutely necessary to take the time and patience to really develop an actor.

Katselas authored two books: Dreams Into Action: Getting What You Want, first published in 1996 by Dove Books, and Acting Class: Take a Seat, which came out earlier this month. Dreams Into Action, a New York Times Bestseller, sought to modify motivational acting exercises to the field of business.

In an interview in the 2007 book Acting Teachers of America, Katselas commented on his experiences as an acting teacher over the years: “I have very special teachers here at the Beverly Hills Playhouse—some have been with me for over twenty-five years. I believe that to make a difference over the long haul, we need to train teachers. I really care about the craft of acting. It’s absolutely necessary to take the time and patience to really develop an actor.”

Posted on December 14th 2018 in Uncategorized

Air Moldova completes airpark with a Brazilian Embraer aircraft

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Air Moldova completes airpark with a Brazilian Embraer aircraft
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Monday, February 11, 2008

Brazilian aircraft maker Embraer on Friday announced it has signed a firm order with Air Moldova for one Embraer 190 jet, to be delivered in March 2010. The contract includes an option on another plane of the same model, Embraer said in a statement. The value of the deal was not disclosed.

At present, renowned companies such as Air France, Lufthansa group and Spanish Iberia Airlines own Embraer 190 jets, specified the representative of Air Moldova. The same source specified that Embraer 190 jet is one of the most economic and optimal aircrafts for operation, and it will be configured in a single-class cabin with 114 seats.

Air Moldova, which links the Moldovan capital, Chi?in?u, to cities in Europe and the Middle East, intends to use the new plane to open new markets.

The Embraer 190 is one of the four members of the E-Jets family. On December 31, the Embraer 170/190 E-Jets had logged 764 firm orders and 786 options.

Embraer is the world’s fourth-largest commercial plane maker. It finished 2007 with a firm order backlog of US$18.8 billion.

Posted on December 12th 2018 in Uncategorized

Oil rig in Gulf of Mexico sinks after explosion; eleven missing

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Oil rig in Gulf of Mexico sinks after explosion; eleven missing
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Friday, April 23, 2010

The oil rig Deepwater Horizon sank yesterday after an explosion Tuesday night that left eleven people missing.

According to an officer from the US Coast Guard, the rig sank sometime in the morning. The rig had caught fire after an explosion of unknown origin occurred two days ago. 115 of the 126 workers on board the time of the explosion have been rescued after evacuating in lifeboats, either by the Coast Guard or from other ships in the area.

The remaining eleven have not been located, although Coast Guard officials have expressed optimism that they are still alive.

The environmental impacts of the explosion and subsequent sinking of the rig are unclear. While up to 13,000 gallons of crude oil per hour has been released from the rig, until now, the effects have been considered minimal, as it had been burned off in the fire. That does have the potential to change, though, according to David Rainey, vice president of the lessor of the rig, BP. The rig, built in 2001 by Hyundai Heavy Industries was owned and operated by Transocean.

The rig was located roughly 50 miles southeast of the coast of Louisiana, and was under lease to BP since 2007. It was completing the construction of a new oil well, and was constructing a layer of cement in the well to reinforce it. This is considered dangerous, as it has the potential to produce an uncontrolled release of case, called a blowout. While the cause of the explosion has yet to be determined, a blowout is considered a possibility.

One survivor of the explosion, who declined to give his name, told the The New York Times that he was laying in bed when the explosion happened. “It caught me by surprise. I’ve been in offshore 25 years, and I’ve never seen anything like that,” he recalled.

Stanley Murray, the father of another survivor named Chad, an electrician, said: “My son had just walked off the drill floor.” However, Murray said that a neighbor did not make it in time, adding that his son told him that the missing eleven workers could not have made it out alive. “The eleven that’s [sic] missing, they won’t find them,” Murray said.

Posted on December 12th 2018 in Uncategorized

Bankruptcy for U.S. automaker GM becomes almost certain after bondholder offers fail

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Bankruptcy for U.S. automaker GM becomes almost certain after bondholder offers fail
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Thursday, May 28, 2009

The United States automobile manufacturing firm General Motors announced on Wednesday that most of its bondholders did not exchange GM’s US$27 billion debt for a ten percent share in the company’s stock.

The automaker, in financial straits, has a June 1 deadline to finish a government restructuring plan that includes plant closures and other debt reduction measures. U.S. President Barack Obama’s administration said it would not give more financial aid to the firm unless 90% of GM’s bondholders would agree on compromises that would significantly reduce the firm’s costs.

“The principal amount of notes tendered was substantially less than the amount required by GM to satisfy the debt reduction requirement,” GM said in a statement.

“They said no. That’s it. They tried. That’s why they’re going to have to file for bankruptcy,” said a university professor from the University of Michigan who specializes in bankruptcy.

Posted on December 12th 2018 in Uncategorized

Viktor Schreckengost dies at 101

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Viktor Schreckengost dies at 101
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Sunday, January 27, 2008

Viktor Schreckengost, the father of industrial design and creator of the Jazz Bowl, an iconic piece of Jazz Age art designed for Eleanor Roosevelt during his association with Cowan Pottery died yesterday. He was 101.

Schreckengost was born on June 26, 1906 in Sebring, Ohio, United States.

Schreckengost’s peers included the far more famous designers Raymond Loewy and Norman Bel Geddes.

In 2000, the Cleveland Museum of Art curated the first ever retrospective of Schreckengost’s work. Stunning in scope, the exhibition included sculpture, pottery, dinnerware, drawings, and paintings.

Posted on December 12th 2018 in Uncategorized

“Lost” actress Elizabeth Mitchell cast in ABC’s “V” pilot

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“Lost” actress Elizabeth Mitchell cast in ABC’s “V” pilot
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Sunday, March 22, 2009

Elizabeth Mitchell, who plays Juliet Burke on the popular series Lost, has been cast in the ABC pilot for V, its remake of the classic science fiction television miniseries, according to an Entertainment Weekly report.

Although ABC and Warner Bros. officials told the magazine she was only cast as a guest star, the announcement led to speculation and concern that the casting could mean Mitchell’s character will be bumped off at the end of Lost‘s fifth season.

EW reports at least two characters will be killed during this season, which ends in May 2009.

During a January interview with New York magazine, Mitchell said of the Shakespearean roots in her name, ” I’m certain it’s not random because they’re never random. It does seem to me that she’s pretty much destined for tragedy, whichever way she goes, no matter how hard she tries to fight against it.”

Juliet, who was introduced in show’s third season, was one of the “Others” who were on the island before the main characters’ plane crashed there. She is currently involved in a love-quadrnagle with characters Sawyer, Jack and Kate.

Posted on December 11th 2018 in Uncategorized

Fußball-Bundesliga 2007–08: Borussia Dortmund vs. Bayern Munich

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Fußball-Bundesliga 2007–08: Borussia Dortmund vs. Bayern Munich
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Sunday, October 28, 2007

October 28, 200717:00 (UTC+1)
Borussia Dortmund 0–0 Bayern Munich Signal Iduna Park, Dortmund Attendance: 80,708 Referee: Markus Merk
Tinga 45’Valdez 61’Valdez 79’Federico 79’Blaszczykowski 83’Klimowicz 83’Klimowicz 90’+1′ Match Report 66′ Sosa 66′ Altintop 70′ Toni 70′ Podolski 88′ van Bommel 88′ Ottl 90’+1′ Schweinsteiger

Bayern Munich remained undefeated in all competitions after a 0-0 draw against Borussia Dortmund. The draw leaves Bayern at the top of the table with 27 points. However, the lead is down to four points after Hamburg’s 1-0 win against Duisburg.

Franck Ribery didn’t pass a late fitness test and didn’t make the 18-man strong matchday squad. Luca Toni, Martin Demichelis an Jose Ernesto Sosa replaced Lukas Podolski, Philipp Lahm and Hamit Altintop. Jose Ernesto Sosa returned after being sidelined for almost two months after ankle surgery.

Bayern Munich and Borussia Dortmund exchanged plenty of chances and almost had a 50/50 possession between them.

Bayern Munich plays Borussia Mönchengladbach at home in the DFB Cup while Borussia Dortmund plays Eintracht Frankfurt in the same competition.

Posted on December 11th 2018 in Uncategorized

Project Management The Basics

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By William Todd

Project overviews define why a project is taking place, what are the business plans, and what the business benefits. A well spent time in planning a project will reduce cost, duration and the quality of the project. A project overview statement gives the following information:

Project name and date

Revision history and versions: includes the date when changes were made & who made the changes.

Sponsor or Customer

Project Manager

Project Objective: describes what the project is going to achieve.

Time estimate: includes the time each team member will spend on that project.

Total costs: includes the capital items and expense items.

Project classification matrix

Assumptions: includes events that are required for the completion of the project but is outside the control of the project team.

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Risks: includes circumstances which can have an adverse impact on the project.

Obstacles or constraints: includes fixed budget, limited resources etc.

Supporting documents: includes copies of business plans, policies, and guidelines.

Approval: includes signatures from concerned project holders.

The application of latest management techniques and systems to execute a project from start to end, to maintain quality, time and cost has given rise to various online project management tools.

Small business is a business owned privately and operated by a small number of employees. Small businesses have worked with email applications, accounting software, contact managers and databases, sales, and bookkeeping. The latest software and systems work together with the programs one is already using.

Operating systems: Windows XP is one of the most advanced desk operating system. Business men can work faster and smarter with this operating system.

Office Systems: The MS office enables one to access information quickly, streamline activities, share and communicate with team members.

Networking and Servers: provides messaging, collaboration, security-enhanced internet access, and protected data storage. Eg. Windows small business server 2003.

Developer tools: obtain quick results, build windows, web, and mobile, communicate and share more with teams, and ensure quality. Eg. Visual studio 2005.

Project manager software helps you plan, monitor, and report on the project. It helps one understand the actual versus planned progress in a project as it happens. It s a web-based system hence one can login from anywhere at anytime. It has the following features:

Dashboard: This one gives a graphical view of the status of one s task online. One can customize one s dashboard and create a unique way to view one s project. With the help of group portfolio one can view different projects at the same time.

Project planner: This helps to create and share plans with team members. One can schedule tasks and assign resources online.

Intelligent reporting: This helps to configure the project status reports with the information one needs.

Manage teams: This helps to create teams, assign tasks, and reallocate tasks.

Track results: This helps to view progress of the project against schedules

Collaborate online: It helps to send emails to other people in the project, share documents, images, and add comments.

Task Manager gives information about programs and processes that run on one s computer. One can see the status of the running programs and end programs that have stopped responding. One can also see graphs and data on CPU and the amount of memory used. If there is more than one person connected to one s computer, one can see who is connected, who is doing a specific task, and also send messages to them. The various tabs used are as follows:

Application tab: Using this tab one can update data, end a program, start a new program, and switch between programs.

Process tab: Using this tab one can assign a process, change priority of running programs, end a process, sort the list of processes, and process column headings.

Performance tab: Using this one can view graphs, number of processes running on the computer, update task manager, change display option, and performance field s overview.

Networking tab: Using this one can view the quality & availability of the network connection. It displays a graphical representation of the network performance.

User tab: displays the users who can access the computer, client name, and session which provides one a name to perform task like sending other user a message or to get connected to other user s session.

Thus build a business or run a project effectively with various aids.

About the Author: Article by William Todd of Dooster.net, a website with the best

task management

and

task management

information on the web.

Source:

isnare.com

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Posted on December 11th 2018 in Software